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Pharmacological properties Selegiline is a selective mao-b inhibitor that also inhibits dopamine reuptake and the dysamine presynaptic receptor. these effects potentiate dopaminergic function in the brain. Selegiline potentiates and prolongs the effect of levodopa, which reduces the dose of the latter. in combination with levodopa preparations, Selegiline increases the duration of the "on … Description Selegiline is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson's disease (sometimes called "shaking palsy" or "paralysis agitans"). This medicine works to increase and extend the effects of levodopa, and may help to slow the progress of Parkinson's disease. This medicine is available only with your doctor's prescription. Eldepryl (Selegiline) 5mg (100 Tablets) is used to treat cognitive dysfunction syndrome and Cushing's disease in dogs and cats. Order Eldepryl (selegiline) 5mg for effective management of Parkinson's symptoms. 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